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NEET Biology: Biomolecules questions with solutions

95 questions with worked solutions.

Questions

Q1. Coenzymes NAD and NADP contain the vitamin

  1. Niacin
  2. Biotin
  3. Thiamine
  4. Vitamin \( B_{12} \) E. Vitamin \( A \)

Answer: Niacin

NAD and NADP are derived from niacin, also called vitamin B3, specifically its nicotinamide component. This vitamin is required to synthesize these electron-carrying coenzymes.

Q2. All the reactions in glycolysis are reversible except

  1. 3 -Phosphoglycerate to 1,3 -Biphosphoglycerate.
  2. Glucose 6-phosphate to fructose - 6-phosphate.
  3. 1,3 -Biphosphoglycerate to glyceraldehyde 3 -P.
  4. Fructose - 6 -phosphate to fructose- 1,6 -diphosphate.

Answer: Fructose - 6 -phosphate to fructose- 1,6 -diphosphate.

Most glycolytic reactions are near-equilibrium and can run in either direction. The phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate is strongly exergonic and is essentially irreversible under cellular conditions.

Q3. Glycogen is stored in

  1. Liver
  2. Muscles
  3. Pancreas
  4. Liver and muscles

Answer: Liver and muscles

Glycogen is the storage form of glucose in animals, and it is mainly stored in the liver and skeletal muscles. The liver helps maintain blood glucose, while muscles use their glycogen for their own energy needs.

Q4. The \( 3^{\prime}-5^{\prime} \) phosphodiester linkages inside a polynucleotide chain serve to join

  1. One nitrogenous base with pentose sugar
  2. One DNA strand with the other DNA strand
  3. one nucleoside with another nucleoside
  4. One nucleotide with another nucleotide

Answer: One nucleotide with another nucleotide

A 3′-5′ phosphodiester bond forms between the phosphate of one nucleotide and the 3′ hydroxyl of the next sugar, creating the backbone of DNA or RNA. Therefore, it joins one nucleotide to another nucleotide.

Q5. Which among the following is correctly categorized?

  1. Troponin and Myosin \( \rightarrow \) Complex proteins in striated muscles
  2. Calcitonin and Thymosin \( \rightarrow \) Thyroid hormones
  3. Pepsin and Prolactin \( \rightarrow \) Digestive enzymes secreted in stomach
  4. Secretin and Rhodopsin \( \rightarrow \) Polypeptide hormones

Answer: Troponin and Myosin \( \rightarrow \) Complex proteins in striated muscles

Troponin and myosin are both proteins associated with the contractile apparatus of striated muscle, so this pairing is correct. The other options mix up hormones, enzymes, and pigments with incorrect categories.

Q6. Tracer elements are

  1. Micro elements
  2. Macro-elements
  3. Radio isotopes
  4. Vitamins

Answer: Radio isotopes

Tracer elements are substances added in very small amounts to track chemical or biological processes. Radioisotopes are ideal tracers because their radiation can be detected without disturbing the system.

Q7. Glycogen is a/an

  1. Polymer of amino acids.
  2. Polymer of fatty acids.
  3. Unsaturated fats.
  4. Polymer of glucose.

Answer: Polymer of glucose.

Glycogen is the main storage polysaccharide in animals, and polysaccharides are long chains of sugar monomers. In glycogen, the repeating monomer is glucose, so it is a polymer of glucose.

Q8. Vitamins are generally involved in forming component of enzyme called

  1. Apoenzyme
  2. Holoenzyme
  3. Prosthetic group
  4. Coenzyme and prosthetic group

Answer: Coenzyme and prosthetic group

Many vitamins are converted into coenzymes, and some vitamin-derived molecules act as prosthetic groups. Since both are non-protein components involved in enzyme function, the best answer is the one that includes both.

Q9. Characteristic smell of urine is due to

  1. Urea
  2. Uric acid
  3. Urinod substancce
  4. Pus

Answer: Urea

Normal urine has a characteristic smell mainly because of urea and its breakdown products. Pus would suggest infection, and uric acid is not the primary cause of the usual urine odor.

Q10. Structure of RNA can be studied by

  1. Feulgen
  2. Toluene blue
  3. x-ray crystallography
  4. chromatography

Answer: x-ray crystallography

X-ray crystallography is used to determine the three-dimensional structure of molecules, including RNA, by analyzing how X-rays diffract through a crystal. The other options are mainly stains or separation methods, not structural determination techniques.

Q11. Which one of the following statements is wrong?

  1. Cellulose
  2. Chitin
  3. Hemicellulose
  4. Peptidoglycan

Answer: Hemicellulose

Cellulose, chitin, and peptidoglycan are classic structural polymers. Hemicellulose is a heterogeneous group of plant cell-wall polysaccharides, not a single structural polymer like the others, so it is the wrong statement here.

Q12. Macro molecule chitin is :

  1. Phosphorus containing polysaccharide
  2. Sulphur containing polysaccharide
  3. Simple polysaccharide
  4. Nitrogen containing polysaccharide

Answer: Nitrogen containing polysaccharide

Chitin is a structural polysaccharide made of N-acetylglucosamine units, so it contains nitrogen. That is why it is classified as a nitrogen-containing polysaccharide.

Q13. Which of the following is a reducing sugar?

  1. galactose
  2. gluconic acid
  3. β-methyl galactoside
  4. sucrose

Answer: galactose

Galactose is a monosaccharide with a free hemiacetal anomeric carbon, so it can open to its aldehyde form and act as a reducing sugar. Gluconic acid is oxidized, β-methyl galactoside is a glycoside with the anomeric carbon blocked, and sucrose is nonreducing because both anomeric carbons are tied up in the glycosidic bond.

Q14. A polysaccharide, which is synthesized and stored in liver cells, is

  1. lactose
  2. galactose
  3. arabinose
  4. glycogen

Answer: glycogen

Glycogen is the main polysaccharide used by animals to store glucose, especially in liver cells. The other options are not storage polysaccharides: lactose is a disaccharide, while galactose and arabinose are monosaccharides.

Q15. In which one of the following groups, all the three are examples of polysaccharides?

  1. Starch, glycogen, cellulose
  2. Sucrose, maltose, cellulose
  3. glucose, fructose, lactose
  4. Galactose, starch, sucrose

Answer: Starch, glycogen, cellulose

Starch, glycogen, and cellulose are all polysaccharides because each is a large polymer made of many glucose units. The other options include mono- or disaccharides such as glucose, fructose, sucrose, maltose, lactose, or galactose.

Q16. Lactose is composed of

  1. Glucose + Glucose
  2. Glucose + Fructose
  3. Fructose + Galactose
  4. Glucose + Galactose

Answer: Glucose + Galactose

Lactose is the milk sugar, and it is a disaccharide made from glucose and galactose. The enzyme lactase breaks it into these two monosaccharides during digestion.

Q17. For its activity, carboxypeptidase requires

  1. zinc
  2. iron
  3. niacin
  4. copper

Answer: zinc

Carboxypeptidase is a zinc-dependent metalloenzyme. The zinc ion helps polarize the substrate and activate a water molecule for hydrolysis of peptide bonds.

Q18. In germinating seeds fatty acids are degraded exclusively in the

  1. proplastids
  2. glyoxysomes
  3. peroxisomes
  4. mitochondria

Answer: glyoxysomes

Glyoxysomes are specialized peroxisomes in germinating seeds that contain enzymes for fatty acid beta-oxidation and the glyoxylate cycle. This lets seedlings convert stored lipids into carbohydrates before photosynthesis begins.

Q19. Uridine, present only in RNA is a

  1. Pyrimidine
  2. Nucleoside
  3. Nucleotide
  4. Purine

Answer: Nucleoside

Uridine consists of a nitrogenous base (uracil) linked to a sugar (ribose), which makes it a nucleoside. A nucleotide would require one or more phosphate groups, and pyrimidine/purine refer only to the base type.

Q20. Proline (symbol Pro or P) is a proteinogenic amino acid that is used in the biosynthesis of proteins.

  1. Proline is the only proteinogenic amino acid with a secondary amine.
  2. The alpha-amino group is attached directly to the main chain.
  3. Proline is unique in that it is the only amino acid where the side chain is connected to the protein backbone twice.
  4. Proline can be considered to be an opposite of Glycine.

Answer: Proline is unique in that it is the only amino acid where the side chain is connected to the protein backbone twice.

Proline is special because its side chain cyclizes back onto the backbone nitrogen, making a ring and connecting to the backbone twice. That structural constraint is what makes the correct statement true.

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