Exams › JEE Advanced › Chemistry › Chemistry in Everyday Life
91 questions with worked solutions.
Q1. Which of the following substances is classified as an antipyretic drug (a fever-reducing agent)?
Answer: Paracetamol
Paracetamol (acetaminophen) is a widely used antipyretic and analgesic drug. Seldane is an antihistamine, Luminal (phenobarbitone) is an anticonvulsant/sedative, and Aspartame is an artificial sweetener.
Answer: All three matchings are correct
Paracetamol (acetaminophen) is a well-known antipyretic and analgesic. Seldane (terfenadine) is a second-generation antihistamine used for allergies. Aspartame is an artificial sweetener made from aspartic acid and phenylalanine methyl ester. All three matchings given in the question stem are correct.
Answer: (A) It contains a beta-lactam (4-membered cyclic amide) ring fused to a thiazolidine ring
Penicillin is a bicyclic molecule consisting of a beta-lactam ring (4-membered cyclic amide, highly strained) fused to a thiazolidine ring (5-membered ring containing sulphur and nitrogen). The beta-lactam ring is essential for antibiotic activity; it irreversibly inhibits the transpeptidase enzyme involved in bacterial cell wall synthesis.
Q4. Which of the following ions, when dissolved in water, reduces the lathering ability of soap?
Answer: Ca²+
Ca²+ (and Mg²+) ions cause water hardness by precipitating soap as insoluble calcium or magnesium salts, thereby reducing lather formation. However, Ca²+ is the primary species specifically mentioned in standard hard-water discussions. Since both Ca²+ and Mg²+ affect lathering, but the canonical answer in most textbooks is Ca²+.
Q5. Which among the following is classified as an antibiotic?
Answer: Ampicillin
All four options relate to antibiotics, but Ampicillin is a specific semi-synthetic broad-spectrum antibiotic of the penicillin group, making it the most precisely defined antibiotic among the choices. Ofloxacin is a fluoroquinolone antibiotic, Aminoglycoside is a class, and Penicillin is a group name.
Answer: Anti-depressant
Noradrenaline (norepinephrine) is a key neurotransmitter in the brain associated with alertness and mood. Its deficiency is linked to clinical depression. Anti-depressants work by increasing the concentration of monoamine neurotransmitters (including noradrenaline and serotonin) at synapses. The other options treat pain (analgesic), inflammation (anti-inflammatory), and allergic responses (antihistamine), none of which address noradrenaline deficiency.
Answer: Indole derivative where -COOH is converted to methyl ester (-CO2CH3) and the amine is protonated as -NH2*HCl salt
SOCl2 is a highly reactive reagent. It converts -COOH to -COCl (acyl chloride) and simultaneously protonates the -NH2 group to give an ammonium chloride salt (-NH3+ Cl-). When methanol is subsequently added, it attacks the acyl chloride to form the methyl ester (-CO2CH3) with release of HCl. The -NH2 group remains as the HCl salt throughout. The indole ring is not chlorinated under these mild conditions.
Q8. Which of the following statements about fluoride ion concentration in drinking water are correct?
Answer: The recommended concentration of fluoride ion in drinking water is 1 ppm.
The optimum fluoride level for dental health is 1 ppm. Below this level dental caries develops; above this level fluorosis (brown mottling) occurs. All three positive statements are individually correct facts from NCERT Chemistry.
Q9. The cleansing action of soap is due to which of the following mechanisms?
Answer: Oil and grease are absorbed into the hydrophobic core of soap micelles and then washed away with water
When soap is dissolved in water, its molecules arrange into micelles: the non-polar hydrocarbon tails cluster inward (hydrophobic core) while the ionic heads face outward (hydrophilic shell). Grease and oily dirt dissolve in the hydrophobic interior of the micelle and are thereby emulsified and rinsed away by water.
Q10. What is the purpose of adding gypsum (CaSO4*2H2O) to cement during its manufacture?
Answer: To slow down the process of setting of the cement
Gypsum is added to cement clinker to retard the setting process by forming ettringite (calcium sulfoaluminate hydrate) on the surface of tricalcium aluminate particles, slowing down their hydration and giving adequate working time.
Q11. Which property of aspirin is responsible for its ability to prevent heart attacks?
Answer: Its ability to inhibit the synthesis of prostaglandins
Aspirin (acetylsalicylic acid) irreversibly acetylates the COX enzyme, blocking the synthesis of thromboxane A2 (a prostaglandin derivative) that promotes platelet aggregation and vasoconstriction. This antiplatelet effect prevents thrombus (clot) formation in coronary arteries, thereby reducing heart attack risk.
Q12. Which property of aspirin is responsible for its use in preventing heart attacks?
Answer: It inhibits the synthesis of prostaglandins
Aspirin prevents heart attacks by inhibiting prostaglandin synthesis via irreversible inhibition of cyclooxygenase (COX) enzyme. This reduces thromboxane A2 production in platelets, decreasing platelet aggregation and blood clot formation.
Q13. Gypsum (CaSO4·2H2O) is added to Portland cement in order to:
Answer: Slow down the setting process
Gypsum reacts with tricalcium aluminate (Ca3Al2O6) in cement to form calcium sulphoaluminate (ettringite), which forms a protective coating on C3A particles. This slows down the initial rapid hydration (flash setting), giving workers adequate time to use the cement.
Answer: NO, NH3
Y is identified as NO because it forms an unstable brown complex with FeSO4 (the brown ring test for NO). Z is NH3, which under the described Al/OH⁻ conditions forms an ammonium salt X; X with Fe2+/H+ in acidic medium generates NO.
Q15. What is the usual range of molecular masses for drug molecules?
Answer: about 100-500 u
Drugs are typically low molecular mass organic compounds, generally in the range of about 100-500 u.
Answer: A->R; B->S; C->P; D->Q
Chloroxylenol (phenol) gives the ferric chloride test (R); norethindrone (terminal alkyne) gives Baeyer's test (S); sulphapyridine (primary aromatic amine) gives the carbylamine test (P); penicillin (carboxylic acid) gives the sodium bicarbonate test (Q).
Q17. A mixture of chloroxylenol and terpineol is an example of which type of substance?
Answer: antiseptic
The chloroxylenol-terpineol mixture is the active constituent of Dettol, a common antiseptic.
Q18. What is the common name of 2-acetoxybenzoic acid (acetylsalicylic acid)?
Answer: Aspirin
2-Acetoxybenzoic acid is acetylsalicylic acid, commonly known as aspirin, an analgesic and antipyretic.
Q19. Which of the following is a bacteriostatic antibiotic?
Answer: Chloramphenicol
Chloramphenicol, tetracycline and erythromycin are bacteriostatic (inhibit growth), while penicillin is bactericidal (kills). The single best/standard answer here is chloramphenicol.
Q20. Antihistamine drugs function as which of the following?
Answer: Antacid and antiallergic
Antihistamines act as both antiallergic agents (H1-blockers like diphenhydramine) and antacids (H2-blockers like ranitidine/cimetidine reduce stomach acid).
Answer: (A), (B) only
(A) and (B) are correct. (C) and (D) are reversed: competitive drugs block the active site, while non-competitive drugs bind the allosteric site.
Q22. Arsenic-based drugs are chiefly used to treat which disease?
Answer: Syphilis
Arsenic-containing drugs such as Salvarsan (arsphenamine) were the classic treatment for syphilis.
Q23. Which of the following drugs contains one or more chiral (stereogenic) carbon atoms?
Answer: Chloramphenicol
Chloramphenicol has two chiral carbon centres (it is the (1R,2R) isomer that is active), so it clearly contains chiral carbons. Among the listed options it is the standard answer.
Answer: Statement I is false but Statement II is true
Statement I is false because inhibitors can also bind at allosteric sites (not only the active site). Statement II is true since some inhibitors bind covalently and irreversibly.
Q25. Aspirin is produced by acetylation of which compound?
Answer: o-hydroxybenzoic acid
Aspirin (acetylsalicylic acid) is formed by acetylating the phenolic -OH of salicylic acid, which is o-hydroxybenzoic acid.
Answer: (a)-(ii), (b)-(i), (c)-(iv), (d)-(iii)
Sucralose is an artificial sweetener (ii), glyceryl ester of stearic acid is associated with synthetic detergent/soap chemistry (i), sodium benzoate is a food preservative (iv), and bithionol is an antiseptic (iii).
Q27. Chloramphenicol is classified as a/an:
Answer: Antibiotic
Chloramphenicol is a broad-spectrum antibiotic, historically important in treating typhoid fever.
Q28. Which of the following pairs correctly combines a non-narcotic analgesic with a narcotic analgesic?
Answer: Aspirin, Morphine
A correct non-narcotic + narcotic pair must contain exactly one of each. Aspirin (non-narcotic) with Morphine (narcotic) fits; the option with Paracetamol+Heroin also fits, but Aspirin+Morphine is the standard intended pairing where aspirin is the classic non-narcotic analgesic.
Q29. How many chlorine atoms are present in one molecule of bithionol?
Answer: 4
Bithionol is 2,2'-thiobis(4,6-dichlorophenol); each of the two phenol rings carries two chlorine atoms, giving four chlorine atoms in total.
Q30. Substances that reduce body temperature (relieve fever) are called:
Answer: Antipyretics
Antipyretics are drugs that lower elevated body temperature (fever).
Q31. Which of the following is used as a food preservative?
Answer: Sodium benzoate
Sodium benzoate is a widely used food preservative; while sorbic and propanoic acids are also preservatives, sodium benzoate is the standard single-best textbook answer.
Answer: (a)-(ii), (b)-(iv), (c)-(i), (d)-(iii)
Cimetidine is an antacid (H2 blocker), alitame an artificial sweetener, novestrol an antifertility drug, and valium (diazepam) a tranquilizer, giving (a)-(ii),(b)-(iv),(c)-(i),(d)-(iii).
Q33. Which of the following drugs is administered to treat hypertension (high blood pressure)?
Answer: Equanil
Equanil (meprobamate) is a tranquilliser used to treat anxiety, tension and hypertension. Salvarsan is an antibacterial, chloroxylenol an antiseptic, and aspirin an analgesic/antipyretic.
Q34. Identify the INCORRECT statement among the following about artificial sweeteners.
Answer: Aspartame is about 550 times sweeter than cane sugar.
Aspartame is roughly 100 times sweeter than cane sugar, not 550, so that statement is incorrect. The values for saccharin (~550-650x), alitame (~2000x) and sucralose (~600x; the ~160x value is also commonly quoted) are within accepted ranges, making aspartame the false statement here.
Q35. Which of the following is classified as a narrow-spectrum antibiotic?
Answer: Penicillin
Penicillin (penicillin G) acts on a limited range of (mainly Gram-positive) bacteria and is the classic narrow-spectrum antibiotic, whereas ofloxacin, ampicillin and chloramphenicol are broad-spectrum.
Q36. The antiseptic chloroxylenol is chemically:
Answer: 4-chloro-3,5-dimethyl phenol
Chloroxylenol (PCMX), the antiseptic in Dettol, is 4-chloro-3,5-dimethylphenol.
Answer: (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii)
Norethindrone is an antifertility drug, Salvarsan an antibiotic, Meprobamate a tranquilizer, and Alitame an artificial sweetener, giving (a)-(iii), (b)-(iv), (c)-(i), (d)-(ii).
Q38. Phenol finds use as which of the following?
Answer: Both (A) and (B)
Dilute phenol acts as an antiseptic on tissue while more concentrated solutions disinfect surfaces, so phenol serves both roles.
Answer: C9H19-C6H4-O-(CH2-CH2-O)5-CH2-CH2OH
The polyethylene-glycol-based ether with no charged head group is the non-ionic detergent commonly used in liquid dishwashing detergents.
Q40. A mixture of chloroxylenol and terpineol functions as a/an:
Answer: antiseptic
Chloroxylenol together with terpineol is the well-known antiseptic formulation (e.g., Dettol) used to kill or prevent the growth of microorganisms on living tissue.
Q41. Bithional is commonly incorporated into soaps as an additive. It acts as a/an:
Answer: antiseptic
Bithional is added to medicated soaps to impart antiseptic (germicidal) properties, reducing odour-causing bacteria on the skin.
Answer: A-Q, B-S, C-R, D-R
Aspirin is an analgesic (and antipyretic), paracetamol is chiefly an antipyretic, while Soframycin and Penicillin are antibiotics. This matches A-Q, B-S, C-R, D-R.
Q43. Which of the following is NOT used as an antioxidant?
Answer: Sodium palmate
BHT, sulphur dioxide and sulphites are common food antioxidants/preservatives. Sodium palmate is a soap (sodium salt of palmitic acid) used as a cleansing agent, not an antioxidant.
Q44. Noradrenaline is classified as a/an:
Answer: Neurotransmitter
Noradrenaline (norepinephrine) is a chemical messenger released at nerve endings to transmit impulses, i.e. a neurotransmitter. Its deficiency is associated with depression, which is why antidepressants act on it, but noradrenaline itself is a neurotransmitter.
Q45. Which artificial sweetener is stable only under cold conditions?
Answer: aspartame
Aspartame is unstable at high (cooking) temperatures, so it is used only in cold foods and soft drinks.
Answer: A-Q, B-Q, C-P, D-S
Penicillin and chloramphenicol are antibiotics; 0.2% phenol is an antiseptic while 1% phenol acts as a disinfectant.
Answer: Statement I is incorrect but statement II is true
Penicillin is bactericidal (it kills bacteria by disrupting cell-wall synthesis), not bacteriostatic, so Statement I is false; its general structure does contain the beta-lactam ring, so Statement II is true.
Answer: A dilute solution of boric acid is a strong antiseptic.
Dilute boric acid is a weak/mild antiseptic, so calling it a 'strong' antiseptic is incorrect; the other three statements are true.
Answer: PhCH2-CH(NH2)-CO2H (phenylalanine)
Aspartame is L-aspartyl-L-phenylalanine methyl ester; complete hydrolysis yields aspartic acid, phenylalanine and methanol. Alanine is NOT a product. Phenylalanine (option A) is one of the products.
Answer: (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)
Furacin is an antiseptic, arsphenamine is an antibiotic, dimetone is a synthetic antihistamine and Valium (diazepam) is a tranquilizer, giving (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii).