StreakPeaked· Practice

ExamsJEE AdvancedChemistry

Which property of aspirin is responsible for its ability to prevent heart attacks?

  1. Its antipyretic (fever-reducing) property
  2. Its analgesic (pain-killing) property
  3. Its action as a blood thinner (anticoagulant)
  4. Its ability to inhibit the synthesis of prostaglandins

Correct answer: Its ability to inhibit the synthesis of prostaglandins

Solution

Aspirin (acetylsalicylic acid) irreversibly acetylates the COX enzyme, blocking the synthesis of thromboxane A2 (a prostaglandin derivative) that promotes platelet aggregation and vasoconstriction. This antiplatelet effect prevents thrombus (clot) formation in coronary arteries, thereby reducing heart attack risk.

Related JEE Advanced Chemistry questions

⚔️ Practice JEE Advanced Chemistry free + battle 1v1 →