Exams › JEE Advanced › Chemistry
Correct answer: Its ability to inhibit the synthesis of prostaglandins
Aspirin (acetylsalicylic acid) irreversibly acetylates the COX enzyme, blocking the synthesis of thromboxane A2 (a prostaglandin derivative) that promotes platelet aggregation and vasoconstriction. This antiplatelet effect prevents thrombus (clot) formation in coronary arteries, thereby reducing heart attack risk.