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ExamsNEETBiology

The enzymes hexokinase which catalyses glucose to glucose-6-phosphate in glycolysis is inhibited by glucose-6-phosphate. This is an example of

  1. competitive inhibition
  2. non-competitive inhibition
  3. feedback allosteric inhibition
  4. positive feedback

Correct answer: feedback allosteric inhibition

Solution

Glucose-6-phosphate is the product of the hexokinase reaction, and it inhibits hexokinase to prevent excess buildup. This is feedback allosteric inhibition because the product regulates an earlier step in the pathway through an allosteric effect.

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