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JEE Main Chemistry: Chemistry in Everyday Life questions with solutions

157 questions with worked solutions.

Questions

Q1. Which of the following compounds is employed in photography?

  1. Sodium sulfite (Na2SO3)
  2. Sodium persulfate (Na2S2O8)
  3. Sodium thiosulfate (Na2S2O3)
  4. Sodium dithionite (Na2S2O4)

Answer: Sodium thiosulfate (Na2S2O3)

Sodium thiosulfate is commonly used in photography as a fixing agent, which helps to remove unexposed silver halides from photographic films and papers, thereby stabilizing the image.

Q2. DDT undergoes a slow transformation to which of the following products?

  1. CCl3-CHO and chlorobenzene
  2. p,p'-Dichlorodiphenylethylene
  3. p,p'-Dichlorodiphenyldichloroethane
  4. p,p'-Dichlorodiphenylchloroethane

Answer: p,p'-Dichlorodiphenylethylene

DDT slowly eliminates HCl (dehydrohalogenation) to form DDE, p,p'-dichlorodiphenyldichloroethylene (p,p'-dichlorodiphenylethylene). This persistent metabolite is what accumulates in the environment.

Q3. Aspirin is formed by acetylating which compound?

  1. p-Dihydroxybenzene
  2. o-Hydroxybenzoic acid
  3. o-Dihydroxybenzene
  4. m-Hydroxybenzoic acid

Answer: o-Hydroxybenzoic acid

Aspirin (acetylsalicylic acid) is made by acetylating the phenolic -OH of o-hydroxybenzoic acid (salicylic acid) with acetic anhydride. The carboxyl group is retained and the OH becomes an acetate ester.

Q4. Denaturation of alcohol refers to the process of adding which of the following to commercial alcohol so that it becomes unfit for drinking?

  1. Adding CuSO4 as the foul-smelling agent and pyridine to impart colour
  2. Adding CuSO4 to impart colour and pyridine as the foul-smelling agent
  3. Adding Cu(OAc)2 and ammonia to render the alcohol unfit for consumption
  4. Adding Cu(OAc)2 and pyridine to render the alcohol unfit for consumption

Answer: Adding CuSO4 to impart colour and pyridine as the foul-smelling agent

Denaturation adds copper sulphate (CuSO4) to impart a blue colour and pyridine to give a foul smell/taste, making the alcohol unfit for drinking.

Q5. Mass poisoning deaths associated with contaminated liquor are mainly caused by the presence of which substance?

  1. Carbonic acid in the liquor
  2. Ethyl alcohol in the liquor
  3. Methyl alcohol in the liquor
  4. Lead compounds in the liquor

Answer: Methyl alcohol in the liquor

Deaths from spurious/contaminated liquor are mainly due to methyl alcohol (methanol), which is metabolised to formaldehyde and formic acid causing blindness and death.

Q6. Arsenic-containing medicines are primarily employed in the management of which disease?

  1. Jaundice
  2. Typhoid fever
  3. Syphilis
  4. Cholera

Answer: Syphilis

Organoarsenic compounds such as Salvarsan (arsphenamine) were the classic chemotherapeutic agents used to treat syphilis. Hence arsenic-containing medicines are primarily associated with syphilis.

Q7. Which of the following is the chemical identity of the antiseptic chloroxylenol?

  1. 4-chloro-3,5-dimethylphenol
  2. 3-chloro-4,5-dimethylphenol
  3. 4-chloro-2,5-dimethylphenol
  4. 5-chloro-3,4-dimethylphenol

Answer: 4-chloro-3,5-dimethylphenol

Chloroxylenol (the active antiseptic in Dettol) is 4-chloro-3,5-dimethylphenol: a phenol with two methyl groups at the 3,5 positions and chlorine para (position 4) to the OH.

Q8. Which of the following is used as a tranquilizing agent?

  1. Promethazine
  2. Valium
  3. Naproxen
  4. Mifepristone

Answer: Valium

Valium (diazepam) is a benzodiazepine tranquilizer used to relieve anxiety and induce calm. Promethazine is an antihistamine, naproxen is an NSAID analgesic, and mifepristone is an anti-progestin, so Valium is the tranquilizing agent.

Q9. Which of the following cannot serve as a fixative in perfumes?

  1. Benzoin
  2. Sandalwood
  3. Glyceryl dinitrate
  4. Glyceryl diacetate

Answer: Glyceryl dinitrate

Perfume fixatives reduce evaporation of volatile components; benzoin (resin), sandalwood oil and glyceryl diacetate (diacetin) all serve as fixatives. Glyceryl dinitrate (nitroglycerin type) is an explosive and is not used as a fixative.

Q10. Detergents are obtained by first treating which starting material with H2SO4 and then neutralizing the product?

  1. cholesterol
  2. lauryl alcohol
  3. cyclohexanol
  4. p-nitrophenol

Answer: lauryl alcohol

Anionic detergents are made by treating a long-chain alcohol such as lauryl alcohol with concentrated H2SO4 to form lauryl hydrogen sulfate, which is then neutralized with NaOH to give sodium lauryl sulfate, a common detergent.

Q11. Which of the following pairings is incorrect? (i) Proteins essential for the body's communication system — Receptors (ii) Drugs that imitate the natural chemical messenger by activating the receptor — Antagonists (iii) Drugs that bind to a receptor and block its normal action — Agonists

  1. (a) (ii) only
  2. (b) (iii) only
  3. (c) (i) and (iii)
  4. (d) (ii) and (iii)

Answer: (d) (ii) and (iii)

Receptors are indeed the body's communication proteins, so (i) is correct. A drug that mimics the natural messenger and activates the receptor is an AGONIST (not antagonist), so (ii) is wrong. A drug that binds and blocks the receptor's normal action is an ANTAGONIST (not agonist), so (iii) is wrong. Thus the incorrect pairings are (ii) and (iii).

Q12. The antiseptic sold under the brand name Dettol is composed of which pair of substances?

  1. o-chlorophenol and terpenol
  2. o-cresol and terpenol
  3. phenol and terpenol
  4. chloroxylenol and terpenol

Answer: chloroxylenol and terpenol

Dettol is a mixture of chloroxylenol (4-chloro-3,5-dimethylphenol), the active antiseptic, together with terpineol. Hence the correct pair is chloroxylenol and terpineol.

Q13. Which of the following is a drug that may be used for pain relief but is known to cause dependence and changes in mood?

  1. Diazepam
  2. Morphine
  3. N-Acetyl-para-aminophenol
  4. Tetrahydrocannabinol

Answer: Morphine

Morphine is an opioid analgesic that effectively alleviates pain but is also associated with a high potential for dependence and can significantly alter mood due to its effects on the brain's reward system.

Q14. Benzalkonium chloride is classified as a

  1. cationic surfactant with antiseptic action
  2. anionic surfactant and soluble in most organic solvents
  3. cationic surfactant and insoluble in most organic solvents
  4. cationic surfactant used as an antimalarial

Answer: cationic surfactant with antiseptic action

Benzalkonium chloride is a quaternary ammonium salt, i.e. a cationic surfactant, widely used as an antiseptic/disinfectant. It is soluble in organic solvents such as alcohol and acetone, so the correct description is 'cationic surfactant with antiseptic action'.

Q15. Amoxicillin is a semisynthetic derivative of which antibiotic?

  1. Penicillin
  2. Streptomycin
  3. Tetracycline
  4. Chloramphenicol

Answer: Penicillin

Amoxicillin is a beta-lactam antibiotic produced by chemically modifying the penicillin nucleus (6-aminopenicillanic acid), so it is a semisynthetic derivative of penicillin.

Q16. Choose the statement that is not correct.

  1. Equanil is employed to manage depression and high blood pressure.
  2. Mifepristone is a synthetic steroid used as the 'morning-after pill'.
  3. A 0.2% phenol solution acts as an antiseptic, whereas a 1.0% phenol solution acts as a disinfectant.
  4. A drug that destroys organisms inside the body is termed bacteriostatic.

Answer: A drug that destroys organisms inside the body is termed bacteriostatic.

A substance that kills/destroys microorganisms is termed bactericidal; bacteriostatic agents only inhibit their growth and multiplication. Hence the statement calling such a drug 'bacteriostatic' is the incorrect one.

Q17. Antibiotics that act chiefly on either Gram-positive bacteria or Gram-negative bacteria are called X. Antibiotics that work against only one specific organism or one particular disease are called Y. What are X and Y?

  1. X = Broad spectrum antibiotics. Y = Narrow spectrum antibiotics.
  2. X = Broad spectrum antibiotics. Y = Limited spectrum antibiotics.
  3. X = Narrow spectrum antibiotics. Y = Limited spectrum antibiotics.
  4. X = Narrow spectrum antibiotics. Y = Broad spectrum antibiotics.

Answer: X = Narrow spectrum antibiotics. Y = Limited spectrum antibiotics.

Antibiotics effective against a range of either Gram-positive or Gram-negative bacteria are NARROW spectrum (broad spectrum acts on both). Antibiotics effective against a single organism or disease are LIMITED spectrum. Hence X = narrow spectrum and Y = limited spectrum.

Q18. A detergent that is structurally biodegradable is expected to have which type of hydrocarbon chain?

  1. A straight-chain alkyl group
  2. A branched alkyl group
  3. A phenyl substituent
  4. A cyclohexyl substituent

Answer: A straight-chain alkyl group

Detergents with straight (linear) alkyl chains are readily broken down by microorganisms and are biodegradable, whereas highly branched chains resist microbial attack and are non-biodegradable. So a biodegradable detergent has a straight-chain alkyl group.

Q19. The term "H1-receptor antagonists" is associated with which of the following?

  1. Antiseptics
  2. Antihistamines
  3. Antacids
  4. Analgesics

Answer: Antihistamines

H1-receptor antagonists are drugs that block the H1 type of histamine receptor, so they act as antihistamines (used for allergies). They are not antiseptics.

Q20. Which one of the following statements is incorrect?

  1. Certain disinfectants may also be applied as antiseptics.
  2. Sulfadiazine is a synthetic antibacterial agent.
  3. Aspirin acts as both an analgesic and an antipyretic.
  4. Polystyrene is used in the manufacture of non-stick cookware.

Answer: Polystyrene is used in the manufacture of non-stick cookware.

The incorrect statement is that polystyrene is used for non-stick cookware - that material is Teflon (PTFE). Sulfadiazine is indeed a synthetic antibacterial sulfa drug, aspirin is both analgesic and antipyretic, and some disinfectants can be used as antiseptics at lower concentration.

Q21. Why are aluminium salts commonly included in most deodorant formulations?

  1. They function as antiperspirants
  2. They work as antibacterial substances
  3. They cover up body odour
  4. They perform all of these roles

Answer: They function as antiperspirants

Aluminium salts such as aluminium chlorohydrate are added to deodorants because they act as antiperspirants: they form a temporary gel plug in the sweat ducts and reduce perspiration, which in turn limits the bacterial breakdown that causes odour.

Q22. What are the chemical signals employed by insects for communication known as?

  1. Pheromones
  2. Hormones
  3. Enzymes
  4. Nucleoproteins

Answer: Pheromones

Pheromones are specialized chemical substances that insects release to communicate with one another, often to signal danger, attract mates, or mark territory, making them essential for social interactions within insect populations.

Q23. Antiseptics and disinfectants either destroy microorganisms or stop their multiplication. Which one of the following statements is incorrect?

  1. Chlorine and iodine are employed as powerful disinfectants.
  2. Weak solutions of boric acid and hydrogen peroxide are strong antiseptics.
  3. Disinfectants damage living tissues.
  4. A 0.2% phenol solution works as an antiseptic, whereas a 1% solution acts as a disinfectant.

Answer: Weak solutions of boric acid and hydrogen peroxide are strong antiseptics.

Weak solutions of boric acid and hydrogen peroxide are not considered strong antiseptics; they are generally milder and less effective than stronger antiseptics, making this statement incorrect.

Q24. Which of the following is not used as an artificial sweetening agent?

  1. Sucralose
  2. Alitame
  3. Saccharin
  4. Sucrose

Answer: Sucrose

Sucrose is a natural sugar found in many plants and is not considered an artificial sweetener, unlike the other options which are synthesized to provide sweetness without the calories of sugar.

Q25. Which of the following best describes a broad-spectrum antibiotic?

  1. Destroys antibodies
  2. Acts only on one specific antigen
  3. Acts on a wide range of antigens
  4. Acts on both antigens and antibodies

Answer: Acts on a wide range of antigens

A broad-spectrum antibiotic is effective against a wide range of disease-causing microorganisms (a wide range of antigens/pathogens), unlike narrow-spectrum antibiotics which act on only a few. Hence it acts on a wide range of antigens.

Q26. Fluoride in drinking water is considered desirable up to about 1 ppm because fluoride helps harden tooth enamel by transforming [3Ca3(PO4)2.Ca(OH)2] into which compound?

  1. [CaF2]
  2. [3(CaF2).Ca(OH)2]
  3. [3(Ca3(PO4)2.CaF2]
  4. [3{(Ca(OH)2.CaF2]

Answer: [3(Ca3(PO4)2.CaF2]

Fluoride enhances the strength of tooth enamel by replacing hydroxide ions in hydroxyapatite, which is represented by the formula [3(Ca3(PO4)2.CaF2], thus forming a more resilient compound that helps prevent cavities.

Q27. Which one of the following types of drugs reduces fever ?

  1. Tranquiliser
  2. Antibiotic
  3. Antipyretic
  4. Analgesic

Answer: Antipyretic

Antipyretics are specifically designed to lower fever by acting on the hypothalamus to regulate body temperature, making them the correct choice for reducing fever.

Q28. Aspirin is known as:

  1. Acetyl salicylic acid
  2. Phenyl salicylate
  3. Acetyl salicylate
  4. Methyl salicylate

Answer: Acetyl salicylic acid

Aspirin is chemically identified as acetyl salicylic acid, which reflects its structure as an acetyl derivative of salicylic acid, making option A the correct choice.

Q29. Which of the following compounds is not an antacid ?

  1. Phenelzine
  2. Ranitidine
  3. Aluminium hydroxide
  4. Cimetidine

Answer: Phenelzine

Phenelzine is a monoamine oxidase inhibitor used primarily as an antidepressant, whereas the other options, including ranitidine, aluminium hydroxide, and cimetidine, are specifically designed to neutralize stomach acid and treat conditions like heartburn and ulcers.

Q30. Which of the following is an anionic detergent?

  1. Cetyltrimethyl ammonium bromide.
  2. Glyceryl oleate.
  3. Sodium stearate.
  4. Sodium lauryl sulphate.

Answer: Sodium lauryl sulphate.

Sodium lauryl sulphate is classified as an anionic detergent because it contains a negatively charged sulfate group, which allows it to effectively reduce surface tension and emulsify oils and fats in water.

Q31. The correct match between Item-I and Item-II is: Item-I (Drug) A. Chloroxylenol B. Norethindrone C. Sulphapyridine D. Penicillin Item-II (Test) p. Carbylamine test q. Sodium hydrogen carbonate test r. Ferric chloride test s. Bayer's test

  1. A → r; B → p; C → s; D → q
  2. A → q; B → s; C → p; D → r
  3. A → r; B → s; C → p; D → q
  4. A → q; B → p; C → s; D → r

Answer: A → r; B → s; C → p; D → q

The correct option matches each drug with its specific test: Chloroxylenol is identified using the Ferric chloride test, Norethindrone is tested with Bayer's test, Sulphapyridine is confirmed through the Carbylamine test, and Penicillin is assessed using the Sodium hydrogen carbonate test.

Q32. The gas leaked from a storage tank of the Union Carbide plant in Bhopal gas tragedy was -

  1. Ammonia
  2. Phosgene
  3. Methyl isocyanate
  4. Methylamine

Answer: Methyl isocyanate

Methyl isocyanate was the toxic gas released during the Bhopal gas tragedy, which caused widespread harm due to its highly reactive and lethal properties.

Q33. The correct match between items of List-I and List-II is [JEE-Main On line-2018] List-I (A) Phenelzine (B) Chloroxylenol (C) Uracil (D) Ranitidine List-II (p) Pyrimidine (q) Furan (r) Hydrazine (s) Phenol

  1. (A)-(s); (B)-(r); (C)-(q); (D)-(p)
  2. (A)-(r); (B)-(s); (C)-(p); (D)-(q)
  3. (A)-(r); (B)-(s); (C)-(q); (D)-(p)
  4. (A)-(s); (B)-(r); (C)-(p); (D)-(q)

Answer: (A)-(r); (B)-(s); (C)-(p); (D)-(q)

Phenelzine is a hydrazine derivative, making it match with (r). Chloroxylenol is a phenolic compound, matching it with (s). Uracil is a pyrimidine, corresponding to (p), and Ranitidine is related to furan, aligning with (q).

Q34. The recommended concentration of fluoride ion in drinking water is up to 1 ppm as fluoride ion is required to make teeth enamel harder by converting [3Ca3(PO4)2.Ca(OH)2] to:

  1. [CaF2]
  2. [3(CaF2).Ca(OH)2]
  3. [3(Ca3(PO4)2.CaF2]
  4. [3(Ca(OH)2.CaF2]

Answer: [3(Ca3(PO4)2.CaF2]

Fluoride ions react with hydroxyapatite in tooth enamel, which is represented by the formula [3Ca3(PO4)2.Ca(OH)2], to form fluorapatite, denoted as [3(Ca3(PO4)2.CaF2]. This conversion enhances the enamel's resistance to decay, making it harder and more durable.

Q35. The correct match between Item I and Item II is: Item I (A) Allosteric effect (B) Competitive inhibitor (C) Receptor (D) Poison Item II (P) M molecule binding to the active site of enzyme (Q) M molecule crucial for communication in the body (R) M molecule binding to a site other than the active site of enzyme (S) M molecule binding to the enzyme covalently (1) (A)→(P); (B)→(R); (C)→(Q); (D)→(S) (2) (A)→(P); (B)→(R); (C)→(S); (D)→(Q) (3) (A)→(R); (B)→(P); (C)→(S); (D)→(Q) (4) (A)→(R); (B)→(P); (C)→(Q); (D)→(S)

  1. (A)→(P); (B)→(R); (C)→(Q); (D)→(S)
  2. (A)→(P); (B)→(R); (C)→(S); (D)→(Q)
  3. (A)→(R); (B)→(P); (C)→(S); (D)→(Q)
  4. (A)→(R); (B)→(P); (C)→(Q); (D)→(S)

Answer: (A)→(R); (B)→(P); (C)→(Q); (D)→(S)

Allosteric effect -> binding to a site other than the active site (R); competitive inhibitor -> binding to the active site (P); receptor -> molecule crucial for communication (Q); poison -> binding covalently (S). So (A)->R, (B)->P, (C)->Q, (D)->S.

Q36. The correct match between Item-I and Item-II is: Item-I (drug) (A) Chloroxylenol (B) Norethindrone (C) Sulphapyridine (D) Penicillin Item-II (test) (P) Carbylamine test (Q) Sodium hydrogen carbonate test (R) Ferric chloride test (S) Bayer's test

  1. A → R; B → S; C → P; D → Q
  2. A → Q; B → P; C → S; D → R
  3. A → Q; B → S; C → P; D → R
  4. A → R; B → P; C → S; D → Q

Answer: A → R; B → S; C → P; D → Q

Chloroxylenol is a phenol -> ferric chloride test (R). Norethindrone has a terminal alkyne -> Baeyer's test (S). Sulphapyridine has a primary aromatic amine -> carbylamine test (P). Penicillin has a -COOH group -> sodium hydrogen carbonate test (Q). So A->R, B->S, C->P, D->Q.

Q37. The compound used in the treatment of lead poisoning is:

  1. desferrioxime B
  2. cis-platin
  3. D-penicillamine
  4. EDTA

Answer: EDTA

EDTA (as its calcium-disodium salt) chelates Pb2+ and is the agent used in the treatment of lead poisoning. cis-platin is anticancer, while D-penicillamine and desferrioxime B remove excess copper and iron.

Q38. Noradrenaline is a/an:

  1. (1) Antacid
  2. (2) Antihistamine
  3. (3) Antidepressant
  4. (4) Neurotransmitter

Answer: (4) Neurotransmitter

Noradrenaline (norepinephrine) is a neurotransmitter released at nerve endings to transmit signals; low levels are linked to depression but the substance itself is a neurotransmitter.

Q39. If you spill a chemical toilet cleaning liquid on your hand, your first aid would be:

  1. aqueous NH3
  2. vinegar
  3. aqueous NaHCO3
  4. aqueous NaOH

Answer: aqueous NaHCO3

Aqueous NaHCO3 (sodium bicarbonate) is a mild alkaline solution that can help neutralize acidic substances, making it suitable for treating spills from acidic toilet cleaning liquids. It can help alleviate irritation and reduce the harmful effects of the chemical on the skin.

Q40. Match the following drugs with their therapeutic actions: (i) Ranitidine (ii) Nardil (Phenelzine) (iii) Chloramphenicol (iv) Dimetane (Brompheniramine) (a) Antidepressant (b) Antibiotic (c) Antihistamine (d) Antacid (e) Analgesic

  1. (i)-(e); (ii)-(a); (iii)-(c); (iv)-(d)
  2. (i)-(d); (ii)-(c); (iii)-(a); (iv)-(e)
  3. (i)-(d); (ii)-(a); (iii)-(b); (iv)-(c)
  4. (i)-(a); (ii)-(c); (iii)-(b); (iv)-(e)

Answer: (i)-(d); (ii)-(a); (iii)-(b); (iv)-(c)

Ranitidine is an antacid (d), Nardil/phenelzine is an antidepressant (a), chloramphenicol is an antibiotic (b), and Dimetane/brompheniramine is an antihistamine (c). So (i)-d, (ii)-a, (iii)-b, (iv)-c.

Q41. The mechanism of action of "Terfenadine" (Seldane) is:

  1. Inhibits the secretion of histamine
  2. Inhibits the action of histamine receptor
  3. Activates the histamine receptor
  4. Helps in the secretion of histamine

Answer: Inhibits the action of histamine receptor

Terfenadine works by blocking histamine H1 receptors, which prevents histamine from exerting its effects, thereby alleviating allergic symptoms.

Q42. The presence of soluble fluoride ion upto 1 ppm concentration in drinking water, is -

  1. harmful for teeth
  2. harmful to bones
  3. harmful to skin
  4. safe for teeth

Answer: safe for teeth

About 1 ppm of soluble fluoride in drinking water is the recommended level; it strengthens enamel (as fluoroapatite) and prevents tooth decay, so it is safe for teeth. Harm (fluorosis) only occurs at much higher concentrations.

Q43. Green chemistry in day-to-day life is the use of: (1) Chlorine for bleaching of paper (2) Large amount of water alone for washing clothes (3) Tetrachloroethene for laundry (4) Liquified CO2 for dry cleaning of clothes

  1. (1) Chlorine for bleaching of paper
  2. (2) Large amount of water alone for washing clothes
  3. (3) Tetrachloroethene for laundry
  4. (4) Liquified CO2 for dry cleaning of clothes

Answer: (4) Liquified CO2 for dry cleaning of clothes

Liquified CO2 is considered a green chemistry option because it is a non-toxic, environmentally friendly solvent that reduces the use of harmful chemicals in dry cleaning processes, making it a more sustainable choice.

Q44. Match List-I with List-II: List-I (Drug) (a) Furacin (b) Arsphenamine (c) Dimetone (d) Valium List-II (Class of Drug) (i) Antibiotic (ii) Tranquilizers (iii) Antiseptic (iv) Synthetic antihistamines Choose the most appropriate match:

  1. (a)-(i), (b)-(iii), (c)-(iv), (d)-(ii)
  2. (a)-(iii), (b)-(iv), (c)-(ii), (d)-(i)
  3. (a)-(ii), (b)-(i), (c)-(iii), (d)-(iv)
  4. (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)

Answer: (a)-(iii), (b)-(i), (c)-(iv), (d)-(ii)

Furacin is an antiseptic used for treating wounds, Arsphenamine is an antibiotic historically used for syphilis, Dimetone is a synthetic antihistamine, and Valium is classified as a tranquilizer, making option D the correct match.

Q45. Which of the following is not a broad-spectrum antibiotic ? (1) Vancomycin (2) Ampicillin (3) Ofloxacin (4) Penicillin G

  1. Vancomycin
  2. Ampicillin
  3. Ofloxacin
  4. Penicillin G

Answer: Penicillin G

Penicillin G is primarily effective against gram-positive bacteria and has limited activity against gram-negative bacteria, making it a narrow-spectrum antibiotic compared to the others listed, which target a wider range of pathogens.

Q46. Drugs used to bind to receptors, inhibiting its natural function and blocking a message are called:

  1. (1) Agonists
  2. (2) Antagonists
  3. (3) Allosterists
  4. (4) Anti histaminis

Answer: (2) Antagonists

Antagonists are substances that attach to receptors and prevent them from activating, thereby blocking the natural function and signaling of those receptors.

Q47. Some drugs bind to a site other than the active site of an enzyme. This site is known as

  1. non-active site
  2. allosteric site
  3. competitive site
  4. therapeutic site

Answer: allosteric site

The allosteric site is a specific location on an enzyme where molecules can bind, leading to a change in the enzyme's shape and activity, distinct from the active site where substrate binding occurs.

Q48. Which one of the following is an example of artificial sweetner ?

  1. Bithional
  2. Alitame
  3. Salvarsan
  4. Lactose

Answer: Alitame

Alitame is a synthetic compound designed to mimic the sweetness of sugar, making it an artificial sweetener, while the other options are not used for sweetening.

Q49. Given below are two statements: One is labelled as Assertion A and the other is labelled as Reason R. Assertion A: Phenolphthalein is a pH dependent indicator, remains colourless in acidic solution and gives pink colour in basic medium. Reason R: Phenolphthalein is a weak acid. It doesn’t dissociate in basic medium. In the light of the above statements, choose the most appropriate answer from the options given below.

  1. Both A and R are true and R is the correct explanation of A
  2. Both A and R are true but R is NOT the correct explanation of A
  3. A is true but R is false
  4. A is false but R is true

Answer: A is true but R is false

Phenolphthalein is colourless in acid and pink in base, so A is true. But it is precisely its dissociation (and ring-opening to the pink quinoid form) in basic medium that produces the colour, so R, claiming it does not dissociate in base, is false. Hence A is true but R is false.

Q50. Statements about Enzyme Inhibitor Drugs are given below: (a) There are Competitive and Non-competitive inhibitor drugs. (b) These can bind at the active sites and allosteric sites. (c) Competitive Drugs are allosteric site blocking drugs. (d) Non-competitive Drugs are active site blocking drugs. Choose the correct answer from the options given below. (A) (a), (d) only (B) (a), (c) only (C) (a), (b) only (D) (a), (b), (c) only

  1. (a), (d) only
  2. (a), (c) only
  3. (a), (b) only
  4. (a), (b), (c) only

Answer: (a), (b) only

Statements (a) and (b) are correct because enzyme inhibitors can indeed be classified into competitive and non-competitive types, and they can bind to both active and allosteric sites on enzymes. Statements (c) and (d) are incorrect as competitive inhibitors bind to active sites, while non-competitive inhibitors do not block the active site but rather bind elsewhere.

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