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The carbylamine reaction transforms a primary amine (R-NH2) into an isocyanide (R-N=C). Which set of reactants and products correctly represents this reaction?

1. R-NH2 reacts with CHCl3 and forms R-N=C.
2. CHCl3 combines with R-NH2 to yield R-N=C.
3. A reaction between R-NH2 and CHCl3 produces R-N=C.
4. R-NH2 and CHCl3 interact to create R-N=C.

Correct answer: R-NH2 reacts with CHCl3 and forms R-N=C.

Solution

The carbylamine reaction involves primary amines (R-NH2), chloroform (CHCl3), and a strong base like KOH to form isocyanides (R-N=C). The reaction is specific to primary amines.

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