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ExamsNEETChemistry

During the Claisen condensation reaction, esters with an α-hydrogen react in the presence of a strong base, resulting in the formation of a β-keto ester. What is the resulting compound?

  1. CH3COOC2H5 transforms into CH3COCH2COOC2H5
  2. CH3COOC2H5 transforms into CH3COCH2COOC2H5 along with H2O
  3. CH3COOC2H5 transforms into CH3COCH2COOC2H5 along with NaOH
  4. CH3COOC2H5 transforms into CH3COCH2COOC2H5 along with CH3OH

Correct answer: CH3COOC2H5 transforms into CH3COCH2COOC2H5

Solution

In Claisen condensation, two ester molecules react to form a β-keto ester. The correct product is CH3COCH2COOC2H5, as no by-products like water, NaOH, or methanol are formed in the main reaction step.

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