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The enzyme DNA ligase connects Okazaki fragments during DNA replication, which proceeds in the 5' to 3' direction. These fragments, formed on the 3' to 5' template strand, combine to create the lagging strand.

1. True
2. False
3. Partially true
4. None of these

Correct answer: True

Solution

Okazaki fragments are short DNA sequences synthesized on the lagging strand during DNA replication. DNA ligase joins these fragments to form a continuous strand, and replication always proceeds in the 5' -> 3' direction.

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