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Two DNA polymerase enzymes operate at the replication fork, with one acting on the leading strand and the other on the lagging strand. On the lagging strand, DNA polymerase synthesizes each Okazaki fragment in the 5'-3' direction. As the replication fork progresses, new Okazaki fragments are formed. The initial Okazaki fragment forms farther from the replication fork, so its elongation occurs in a direction moving away from the fork.

1. (a)
2. (b)
3. (c)
4. (d)

Correct answer: (c)

Solution

The statement in option (c) is correct as it accurately describes the mechanism of DNA replication. DNA polymerase synthesizes the leading strand continuously and the lagging strand discontinuously in the form of Okazaki fragments, which are synthesized in the 5'-3' direction away from the replication fork.

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