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The semi-conservative model of DNA replication was initially demonstrated in the bacteria Escherichia coli by researchers Matthew Meselson and Franklin Stahl.

1. (a)
2. (b)
3. (c)
4. (d)

Correct answer: (a)

Solution

The semi-conservative model of DNA replication was experimentally demonstrated by Meselson and Stahl in Escherichia coli using isotopic labeling with nitrogen isotopes (N-15 and N-14).

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