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In eukaryotic cells, transcription involves three distinct RNA polymerases. (i) RNA polymerase I is involved in the transcription of rRNA genes. (ii) RNA polymerase II synthesizes hnRNA. (iii) RNA polymerase III is responsible for producing tRNA and 5S rRNA. Which of the following statements is accurate?

1. RNA polymerase I is responsible for transcribing rRNA genes.
2. RNA polymerase II is involved in the synthesis of hnRNA.
3. RNA polymerase III transcribes tRNA and 5S rRNA.
4. All of the above statements are correct.

Correct answer: All of the above statements are correct.

Solution

Each statement matches the known division of labor among eukaryotic RNA polymerases: Pol I makes most rRNA, Pol II makes hnRNA/pre-mRNA, and Pol III makes tRNA and 5S rRNA. Since all three are correct, the combined choice is right.

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