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Two microbes found to be very useful in genetic engineering are:

1. Vibrio cholerae and a tailed bacteriophage
2. Diplococcus sp. and Pseudomonas sp.
3. Crown gall bacterium and Caenorhabditis elegans
4. Escherichia coli and Agrobacterium tumefaciens

Correct answer: Escherichia coli and Agrobacterium tumefaciens

Solution

Escherichia coli is widely used to clone and amplify recombinant DNA because it grows quickly and is easy to manipulate. Agrobacterium tumefaciens is valuable because it naturally transfers T-DNA into plant cells, making it a key tool in plant genetic engineering.

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