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ExamsNEETBiology

Under which of the following conditions will there be no change in the reading frame of following mRNA? 5′ AACAGCGCGUGCUAUU 3′

  1. Insertion of G at 5th position
  2. Deletion of G from 5th position
  3. Insertion of A and G at 4th and 5th positions respectively
  4. Deletion of GGU from 7th, 8th and 9th positions

Correct answer: Deletion of GGU from 7th, 8th and 9th positions

Solution

A reading frame stays unchanged when the number of nucleotides inserted or deleted is a multiple of 3. Deleting GGU removes exactly three bases, so the codon grouping downstream is preserved.

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