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During transcription holoenzyme RNA polymerase binds to a DNA sequence and the DNA assumes a saddle like structure at that point. What is that sequence called?

1. AAAT box
2. TATA box
3. GGTT box
4. CAAT box

Correct answer: TATA box

Solution

The TATA box is a promoter sequence recognized during transcription initiation, and binding there helps locally unwind and bend the DNA into the characteristic saddle-like shape. This makes it easier for RNA polymerase and transcription factors to assemble at the start site.

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