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Protein helping in opening of DNA double helix in form of replication fork is

1. DNA gyrase
2. DNA polymerase I
3. DNA ligase
4. DNA topoisomerase

Correct answer: DNA topoisomerase

Solution

DNA topoisomerase helps open the DNA double helix by relieving supercoiling and torsional stress during replication. By temporarily breaking and rejoining DNA strands, it allows the replication fork to progress smoothly.

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