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Out of A-T, G-C pairing, bases of DNA may exist in alternate valency state owing to arrangement called

1. analogue substitution
2. tautomerisational mutation
3. frame-shift mutation
4. point mutation

Correct answer: tautomerisational mutation

Solution

DNA bases can occasionally shift into rare tautomeric forms, altering their pairing preferences. This can make A pair with C or G pair with T, which is why the phenomenon is called tautomerisational mutation.

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