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In a mutational event, when adenine is replaced by guanine, it is a case of:

1. frame shift mutation
2. transcription
3. transition
4. transversion

Correct answer: transition

Solution

The correct answer is transition because adenine and guanine are both purines, and a substitution between two purines is called a transition. Transversions occur between a purine and a pyrimidine, while frame shifts involve insertions or deletions.

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