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The transforming principle of Pneumococcus as found out by Avery, MacLeod and McCarty was

1. mRNA
2. DNA
3. protein
4. polysaccharide

Correct answer: DNA

Solution

Avery, MacLeod, and McCarty demonstrated that the transforming principle in Pneumococcus was DNA. Their extracts lost transforming ability only when treated with DNase, proving DNA carried the genetic information.

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