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ExamsNEETBiology

During transcription, RNA polymerase holoenzyme binds to a gene promoter and assumes a saddle-like structure, what is it’s DNA-binding sequence?

  1. AATT
  2. CACC
  3. TATA
  4. TTAA

Correct answer: TATA

Solution

The promoter region often contains a TATA box, an AT-rich DNA sequence that helps RNA polymerase holoenzyme bind and correctly initiate transcription. Among the options, TATA is the canonical promoter-binding sequence.

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