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Transformation experiment was first performed with which bacteria?

1. E. coli
2. Diplococcus pneumoniae
3. Salmonella
4. Pasteurella pestis

Correct answer: Diplococcus pneumoniae

Solution

The first transformation experiment is credited to Griffith, who worked with pneumococci (Diplococcus pneumoniae). He showed that nonvirulent bacteria could be transformed into virulent forms by material from heat-killed virulent cells.

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