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Change in single base pair of DNA is also a type of mutation called point mutation. It is a type of mutation that causes the replacement of a single nucleotide with another nucleotide of the genetic material, DNA or RNA. For example, a point mutation is the cause of sickle cell disease.
- (a) True
- (b) False
- (c) Cannot be determined
- (d) None of these
Correct answer: (a) True
Solution
The statement is correct because a point mutation involves a change in one base pair or one nucleotide. Sickle cell disease is a well-known example caused by a single-base substitution in the beta-globin gene.
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