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During the transmission of nerve impulse through a nerve fibre, the potential on the inner side of the plasma membrane has which type of electric change?

1. First positive, then negative and continue to be positive
2. First negative, then positive and continue to be negative
3. First positive, then negative and again back to positive
4. First negative, then positive and again back to negative

Correct answer: First negative, then positive and again back to negative

Solution

At rest, the inner side of the nerve membrane is negative relative to the outside. During an impulse, sodium influx reverses the polarity so the inside becomes positive, and then potassium efflux restores the original negative state.

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