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The ABO blood group system is the most important blood type system (or blood group system) in human blood transfusion. It is named ABO and not ABC, because blood group O (or blood group zero in some countries) individuals do not have either A or B antigens on the surface of their RBCs, but their blood serum contains IgM anti-A antibodies and anti-B antibodies against the A and B blood group antigens. Therefore, a group O individual can receive blood only from a group O individual, but can donate blood to individuals of any ABO blood group (i.e., A, B, O or AB).

1. Blood group O individuals lack A and B antigens.
2. Blood group O individuals can donate blood to any ABO group.
3. Blood group O individuals have anti-A and anti-B antibodies.
4. All of the above.

Correct answer: All of the above.

Solution

Each listed statement matches the ABO facts for group O: no A or B antigens on red cells, anti-A and anti-B antibodies in serum, and universal red-cell donation within the ABO system. Since A, B, and C are all true, the correct choice is the one that includes all of them.

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