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NADP+ is reduced to NADPH in

1. HMP
2. Calvin Cycle
3. glycolysis
4. EMP

Correct answer: HMP

Solution

In the HMP shunt (pentose phosphate pathway), glucose-6-phosphate is oxidized and NADP+ is reduced to NADPH. This pathway’s main role is to produce NADPH for reductive biosynthesis and antioxidant defense.

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