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Which of the following is essential for conversion of pyruvic acid into acetyl Co-A?

1. LAA
2. NAD
3. TPP
4. All of these

Correct answer: All of these

Solution

Conversion of pyruvate to acetyl-CoA is carried out by the pyruvate dehydrogenase complex, which requires multiple cofactors. Lipoic acid, NAD, and TPP all participate in the reaction, so the correct choice is all of these.

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