StreakPeaked· Practice

ExamsNEETBiology

Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain (DNA). While exonucleases hydrolyse terminal phosphodiester bonds in a polynucleotide chain (DNA).

  1. Endonucleases hydrolyse terminal bonds.
  2. Exonucleases hydrolyse internal bonds.
  3. Endonucleases hydrolyse internal bonds.
  4. Exonucleases hydrolyse both internal and terminal bonds.

Correct answer: Endonucleases hydrolyse internal bonds.

Solution

Endonucleases cleave phosphodiester bonds within a nucleic acid chain, not at the ends. Exonucleases act on terminal bonds, removing nucleotides from the 5' or 3' end.

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