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Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain (DNA). While exonucleases hydrolyse terminal phosphodiester bonds in a polynucleotide chain (DNA).
- Endonucleases hydrolyse terminal bonds.
- Exonucleases hydrolyse internal bonds.
- Endonucleases hydrolyse internal bonds.
- Exonucleases hydrolyse both internal and terminal bonds.
Correct answer: Endonucleases hydrolyse internal bonds.
Solution
Endonucleases cleave phosphodiester bonds within a nucleic acid chain, not at the ends. Exonucleases act on terminal bonds, removing nucleotides from the 5' or 3' end.
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