Exams › NEET › Biology

What base is responsible for hot spots for spontaneous point mutations?

1. Adenine
2. 5-bromouracil
3. 5-methylcytosine
4. Guanine

Correct answer: 5-methylcytosine

Solution

5-methylcytosine is prone to spontaneous deamination, producing thymine and creating a T:G mismatch. This makes methylated CpG sites common mutation hot spots.

Related NEET Biology questions

• Which of the following is a transcription factor produced by a regulatory gene?
• Which of the following combination is false?
• Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage?
• If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6 × 10⁹ bp, then the length of the DNA is approximately
• Which of the following RNAs should be most abundant in animal cell?
• The final proof for DNA as the genetic material came from the experiments of:

⚔️ Practice NEET Biology free + battle 1v1 →