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A nonsense mutation is the one which stops polypeptide synthesis due to formation of a terminating or nonsense codon e.g. ATT (UAA), ATC (UAG), ACT (UGA). The lactose or lac operon of Escherichia coli contains structural genes (z, y, a). If y codes for termination of polypeptide chain then only the product of 'z' gene transcribe to form β galactosidase.

1. True
2. False
3. Partially true
4. None of these

Correct answer: True

Solution

A nonsense mutation is a type of mutation that results in a premature stop codon, leading to the termination of polypeptide synthesis. In this case, the y gene codes for a termination codon, so the product of the z gene will not be translated.

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