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Which of the following steps of respiration is amphibolic?

1. Glycolysis
2. Oxidative decarboxylation of pyruvate
3. TCA cycle
4. Oxidative phosphorylation

Correct answer: TCA cycle

Solution

The TCA cycle is amphibolic because it oxidizes acetyl-CoA to generate energy and also provides intermediates used in biosynthesis. The other steps are mainly catabolic energy-yielding processes.

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