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Which functional group participates in disulphide bond formation in proteins?

1. Thioester
2. Thioether
3. Thiol
4. Thiolactone

Correct answer: Thiol

Solution

The thiol (-SH) group in cysteine residues of proteins participates in disulphide bond formation through oxidation, linking two cysteine molecules to form a disulphide bridge (-S-S-).

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