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Which of the following reactions is appropriate for converting acetamide to methanamine?

1. Hoffmann hypobromamide reaction
2. Stephens reaction
3. Gabriel's phthalimide synthesis
4. Carbylamine reaction

Correct answer: Hoffmann hypobromamide reaction

Solution

The Hoffmann hypobromamide reaction is used to convert amides like acetamide into primary amines like methanamine by treating them with bromine and a strong base.

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