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Down's syndrome arises from chromosomal non-disjunction, which refers to the failure of homologous X chromosomes to separate during anaphase-I of meiosis, resulting in both X chromosomes moving to one pole while the opposite pole receives none.

1. True
2. False
3. Cannot be determined
4. None of these

Correct answer: True

Solution

Non-disjunction refers to the failure of homologous chromosomes or sister chromatids to separate properly during meiosis, leading to aneuploidy. The description provided in the question aligns with this definition, making the statement true.

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