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Lathyrism which is caused by consumption of Khesari dal is a disease characterised by

1. reproductive failure, susceptibility to diabetes mellitus and skeletal abnormalities
2. retardation of body growth, precocious puberty and renal dysfunction
3. mental retardation, delay in the onset of puberty and cardiovascular abnormalities
4. gross skeletal deformation and thinning of collagen fibres and fibrils

Correct answer: gross skeletal deformation and thinning of collagen fibres and fibrils

Solution

Lathyrism from Khesari dal is classically linked to defective connective tissue formation, especially abnormal collagen cross-linking. This leads to gross skeletal deformities and thinning of collagen fibres and fibrils.

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