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Drug called ‘Heroin’ is synthesised by:

1. methylation of morphine
2. acetylation of morphine
3. glycosylation of morphine
4. nitration of morphine

Correct answer: acetylation of morphine

Solution

Heroin is diacetylmorphine, produced by acetylating the hydroxyl groups of morphine. This modification increases lipid solubility, which is why the acetylation route is correct.

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