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At which stage of HIV infection does one usually show symptoms of AIDS?

1. When the infecting retrovirus enters host cells
2. When viral DNA is produced by reverse transcriptase
3. When HIV replicates rapidly in helper T-lymphocytes and damages large number of these
4. Within 15 day of sexual contact with an infected person

Correct answer: When HIV replicates rapidly in helper T-lymphocytes and damages large number of these

Solution

AIDS symptoms appear in the late stage of HIV infection, when the virus has multiplied extensively in helper T-lymphocytes and destroyed many of them. This severe loss of CD4+ cells weakens immunity enough for opportunistic infections and other AIDS features to develop.

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