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Which of the following statements is not true for cancer cells in relation to mutations?

1. Mutations in proto-oncogenes accelerate the cell cycle.
2. Mutations destroy telomerase inhibitor.
3. Mutations inactivate the cell control.
4. Mutations inhibit production of telomerase.

Correct answer: Mutations inhibit production of telomerase.

Solution

Cancer cells typically maintain or increase telomerase activity so they can keep dividing without shortening their chromosomes. Therefore, a mutation that inhibits telomerase production would oppose cancer cell survival, making it the statement that is not true.

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