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Transplantation of tissues/organs fails often due to non-acceptance by the patient’s body. Which type of immune-response is responsible for such rejections?

1. Cell-mediated immune response
2. Hormonal immune response
3. Physiological immune response
4. Autoimmune response

Correct answer: Cell-mediated immune response

Solution

Transplant rejection is mainly caused by T lymphocytes, which mount a cell-mediated immune response against donor antigens. This response can destroy graft cells and lead to failure of the transplant.

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