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One child is haemophilic (sex-linked trait), while its fraternal twin brother is normal. Which one of the following informations is most appropriate?

1. The mother must have been heterozygous
2. The child is a monozygotic twin
3. The other child is female and the father is haemophilic
4. The haemophilic child is a male

Correct answer: The haemophilic child is a male

Solution

Hemophilia is an X-linked recessive trait, so a child who is affected is typically male because males have only one X chromosome. Since the twins are fraternal and one is normal, the affected twin being male is the most appropriate statement.

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