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Which of the following is correct match?

1. Down's syndrome — 21st chromosome
2. Sickle cell anaemia — X-chromosome
3. Haemophilia — Y-chromosome
4. Parkinson disease — X & Y chromosome

Correct answer: Down's syndrome — 21st chromosome

Solution

Down syndrome is caused by trisomy 21, meaning there are three copies of chromosome 21. The other options are incorrect because sickle cell anaemia is autosomal recessive, haemophilia is X-linked, and Parkinson disease is not matched to X and Y chromosomes.

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