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A normal woman, whose father was colour-blind is married to a normal man. The sons would be:

1. 75% colour-blind
2. 50% colour-blind
3. all normal
4. all colour-blind

Correct answer: 50% colour-blind

Solution

Colour blindness is X-linked recessive. A normal woman with a colour-blind father must be a carrier (X^N X^c), and a normal man is X^N Y, so half of the sons inherit X^c from the mother and are colour-blind.

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