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ExamsNEETBiology

A man with a certain disease marries a normal woman. They have eight children (3 daughters and 5 sons). All the daughters suffer from their father's disease but none of the sons are affected. Which of the following mode of inheritance do you suggest for this disease?

  1. Sex-linked recessive
  2. Sex-linked dominant
  3. Autosomal dominant
  4. Sex-limited recessive

Correct answer: Sex-linked dominant

Solution

An affected father gives his X chromosome to all daughters and his Y chromosome to all sons. If the disease is X-linked dominant, every daughter who receives the affected X will be affected, while sons are not affected from the father’s X because they inherit his Y.

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