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Sickle cell anaemia has not been eliminated from the African population because:

1. it is not a fatal disease
2. it provides immunity against malaria
3. it is controlled by dominant genes
4. it is controlled by recessive genes

Correct answer: it provides immunity against malaria

Solution

The sickle-cell allele remains in African populations because people with one copy have increased resistance to malaria. This heterozygote advantage keeps the allele in the gene pool despite the severe disease in homozygotes.

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