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Down’s syndrome in humans is due to

1. Two ‘Y’ chromosomes
2. Three ‘X’ chromosomes
3. Three copies of chromosome 21
4. Monosomy

Correct answer: Three copies of chromosome 21

Solution

Down’s syndrome is caused by trisomy 21, meaning there are three copies of chromosome 21 instead of the usual two. This extra genetic material leads to the characteristic features of the condition.

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