If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

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Accepted Answer

25%. If both parents are carriers, their genotypes are typically Aa × Aa. The offspring genotypes are AA, Aa, Aa, and aa, so only 1 out of 4 is affected. That makes the chance of an affected child 25%.

If both parents are carriers for thalassemia, which is an autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

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