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An abnormal human baby with ‘XXX’ sex chromosomes was born due to :

1. formation of abnormal ova in the mother
2. fusion of two ova and one sperm
3. fusion of two sperms and one ovum
4. formation of abnormal sperms in the father

Correct answer: formation of abnormal ova in the mother

Solution

An XXX karyotype most commonly results when the mother produces an abnormal ovum containing two X chromosomes, and a normal X-bearing sperm fertilizes it. This gives a zygote with three X chromosomes.

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