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Crossing over that results in genetic recombination in higher organisms occurs between

1. sister chromatids of a bivalent
2. non-sister chromatids of a bivalent
3. two daughter nuclei
4. two different bivalents

Correct answer: non-sister chromatids of a bivalent

Solution

Crossing over occurs in prophase I of meiosis between homologous chromosomes that form a bivalent. The actual exchange is between non-sister chromatids, because sister chromatids are identical copies and do not create new allele combinations.

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