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Extrusion of second polar body from egg nucleus occurs:

1. after entry of sperm but before fertilisation
2. before entry of sperm into ovum
3. simultaneously with first cleavage
4. after fertilisation

Correct answer: after entry of sperm but before fertilisation

Solution

Entry of the sperm activates the secondary oocyte to complete meiosis II, which leads to extrusion of the second polar body. This happens before fertilisation is completed, since fertilisation includes pronuclear fusion after these meiotic events.

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