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Cornea transplant in humans is almost never rejected. This is because:

1. its cells are least penetrable by bacteria
2. it has no blood supply
3. it is composed of enucleated cells
4. it is a non-living layer

Correct answer: it has no blood supply

Solution

The cornea is avascular, so immune cells and antibodies in the bloodstream have limited access to it. This makes immune rejection much less likely than in vascularized transplanted tissues.

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