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Which of the following hormones can play a significant role in osteoporosis?

1. Aldosterone and Prolactin
2. Progesterone and Aldosterone
3. Parathyroid hormone and Prolactin
4. Estrogen and Parathyroid hormone

Correct answer: Estrogen and Parathyroid hormone

Solution

Estrogen helps maintain bone density by limiting osteoclast activity, so low estrogen accelerates bone loss. Parathyroid hormone can increase bone resorption when elevated, making it a key factor in osteoporosis.

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