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The principal nitrogenous excretory compound in humans is synthesised

1. in kidneys but eliminated mostly through liver
2. in kidneys as well as eliminated by kidneys
3. in liver and also eliminated by the same through bile
4. in the liver, but eliminated mostly through kidneys

Correct answer: in the liver, but eliminated mostly through kidneys

Solution

Humans convert toxic ammonia into urea in the liver via the urea cycle. Urea then travels in the blood to the kidneys, which remove most of it in urine.

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